Ocular Toxoplasmosis

A disease that results from infection by a parasite.

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Toxoplasma gondii is a protozoan (single cell organism) that lives within other cells (parasite). There are two types of disease that affect the eyes, congenital and acquired toxoplasmosis. Toxoplasmosis is the most common cause of inflammation in the back part of the eye. Congenital Toxoplasmosis occurs due to maternal infection while pregnant. Acquired Toxoplasmosis occurs to exposure from cats (the definitive host) or the ingestion of raw meat.

Symptoms can include:

  • Unilateral floaters
  • Blurred vision

Treatment options include:

  • Drug regimen

The goal of this treatment is to control the infection and limit the resulting scarring. While there is no consensus on the best treatment, there is agreement that treatment should last a minimum of six weeks.

The classic treatment is a triple drug regimen consisting of sulfadiazine, pyramethamine (Daraprim), and folinic acid. However, side effects are common and blood tests have to be performed to monitor for toxicity.

Oral corticosteroids are often used after the antibiotics have been started to reduce inflammation.

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